Benzodiazepines are a class of drugs generally used for treating anxiety; nonetheless they also are effective for several other conditions. The exact mechanism of action of benzos is not known; nonetheless they apparently work by affecting neurotransmitters in the brain, chemicals that nerve fibres release in order to communicate with other nearby nerves. One of these neurotransmitters is gamma-aminobutyric acidity (GABA), a neurotransmitter that suppresses the activity of nerves. Scientists assume that increased activity of nerves may be the reason behind anxiousness and other psychological disorders, and benzodiazepines decrease the activity of nerves in the mind and spine cord by boosting the effects of GABA.
For what conditions are benzodiazepines used?
Benzodiazepines are used for treating insomnia or trouble sleeping, seizures (convulsions), and anxiety and panic. They also are used for panic attacks, depression, and nausea and vomiting, alcohol withdrawal and drug associated agitation, muscle relaxation, sedation prior to surgery or diagnostic procedures, and general anesthesia.
Two serious concerns of benzodiazepine remedy are the potential for abuse and the intro of physical dependence. Even though intentional abuse of pharmaceutical drug benzodiazepines is relatively unheard of in the general human population, it should be used more cautiously in people who have a history of medication abuse because they are at the greatest risk for seeking benzodiazepines to experience a “high”.Benzodiazepines are rarely the sole street drug, and abusers usually incorporate benzodiazepines with other drugs to improve the effect.
For example, benzodiazepines are combined with certain opioids, a course of strong prescription pain relievers, to enhance the euphoric effects. Among abusers, diazepam (Valium) and alprazolam (Xanax) are most popular because of their fast onset. For most patients, use of a benzodiazepine for a period of several months would not seem to be to cause issues of addiction, tolerance, or issues in stopping the medication when it is no longer needed. Yet , several months of use significantly enhances the risk for dependency, tolerance, and look of withdrawal symptoms with medication dosage reduction or termination of therapy.
The dangers of benzodiazepine habit are many. Airport terminal cases of overdose have been reported with the use of benzodiazepines. Every year benzodiazepine overdose plays a role in a significant number of trips to the unexpected emergency room and hospital vestibule. The antidote for benzodiazepine overdose is flumazenil (Romazicon). To treat benzodiazepine overdose, flumazenil is injected swiftly into the vein.
Exactly what are the dangers of benzodiazepine withdrawal?
When benzodiazepine treatment is stopped abruptly, patients may develop withdrawal symptoms. Factors that raise the risk and severity of drawback symptoms include high dosages and permanent benzodiazepine use. In addition, withdrawal symptoms tend to occur previously with benzodiazepines with brief elimination half-lives.
Prompt reputation and treatment of benzodiazepine withdrawal is crucial as this disorder may be life threatening. Benzodiazepine withdrawal is treated with intravenous benzodiazepines such as diazepam which tends to work over a longer period of time.